Volume 68, Issue S3 p. S11-S19
Clinical Investigation

Measurement and Structure of Cognition in the Longitudinal Aging Study in India–Diagnostic Assessment of Dementia

Alden L. Gross PhD, MHS

Corresponding Author

Alden L. Gross PhD, MHS

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland

Address correspondence to Alden L. Gross, PhD, MHS, Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 2024 E Monument St, Baltimore, MD 21205. E-mail: [email protected], Twitter: @Alden_GrossSearch for more papers by this author
Pranali Y. Khobragade MD

Pranali Y. Khobragade MD

Center for Economic and Social Research, University of Southern California, Los Angeles, California

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Erik Meijer PhD

Erik Meijer PhD

Center for Economic and Social Research, University of Southern California, Los Angeles, California

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Judith A. Saxton PhD

Judith A. Saxton PhD

Center for Economic and Social Research, University of Southern California, Los Angeles, California

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First published: 20 August 2020
Citations: 12

Abstract

OBJECTIVES

To test whether a relatively complex model of human cognitive abilities based on Cattell-Horn-Carroll (CHC) theory, developed mainly in English-speaking samples, adequately describes correlations among tests in the Longitudinal Aging Study in India–Diagnostic Assessment of Dementia (LASI-DAD), and to develop accurate measures of cognition for older individuals in India.

DESIGN

LASI-DAD participants were recruited from participants aged 60 years and older from 14 states in the core LASI survey, with a stratified sampling design.

SETTING

Participants were interviewed at home or in a participating hospital, according to their preferences.

PARTICIPANTS

Community-residing older adults aged 60 years and older (N = 3,224).

MEASUREMENTS

A variety of cognitive tests were administered during two pretests and chosen for their appropriateness for measuring cognition in older adults in India and suitability for calibration with the core LASI survey and the Harmonized Cognitive Assessment Protocol.

RESULTS

We evaluated the factor structure of the test battery and its conformity with a classical CHC factor model that incorporated measurement models for general cognition, five broad domains (orientation, executive functioning, language/fluency, memory, and visuospatial), and five narrow domains (reasoning, attention/speed, immediate memory, delayed memory, and recognition memory) of cognitive performance. Model fit was adequate (root mean square error of approximation = 0.051; comparative fit index = 0.916; standardized root mean squared residual = 0.060).

CONCLUSION

We demonstrated configural factorial invariance of a cognitive battery in the Indian LASI-DAD using CHC theory. Broad domain factors may be used in future research to rank individuals with respect to cognitive performance and classify cognitive impairment. J Am Geriatr Soc 68:S11-S19, 2020.