Volume 39, Issue 11 p. 1065-1070

Effects of Exercise Training on Bone Density in Older Men and Women

James A. Blumenthal PhD

Corresponding Author

James A. Blumenthal PhD

Departments of Psychiatry, Medicine, and Radiology and The Center for Living, Duke University Medical Center, Durham, North Carolina.

Duke University Medical Center, Box 3119, Durham, NC 27710.Search for more papers by this author
Charles F. Emery PhD

Charles F. Emery PhD

Departments of Psychiatry, Medicine, and Radiology and The Center for Living, Duke University Medical Center, Durham, North Carolina.

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David J. Madden PhD

David J. Madden PhD

Departments of Psychiatry, Medicine, and Radiology and The Center for Living, Duke University Medical Center, Durham, North Carolina.

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Susan Schniebolk MPH

Susan Schniebolk MPH

Departments of Psychiatry, Medicine, and Radiology and The Center for Living, Duke University Medical Center, Durham, North Carolina.

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Margaret W. Riddle MS

Margaret W. Riddle MS

Departments of Psychiatry, Medicine, and Radiology and The Center for Living, Duke University Medical Center, Durham, North Carolina.

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Frederick R. Cobb MD

Frederick R. Cobb MD

Departments of Psychiatry, Medicine, and Radiology and The Center for Living, Duke University Medical Center, Durham, North Carolina.

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Michael Higginbotham MB

Michael Higginbotham MB

Departments of Psychiatry, Medicine, and Radiology and The Center for Living, Duke University Medical Center, Durham, North Carolina.

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R. Edward Coleman MD

R. Edward Coleman MD

Departments of Psychiatry, Medicine, and Radiology and The Center for Living, Duke University Medical Center, Durham, North Carolina.

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First published: November 1991
Citations: 37

Preparation of this manuscript was supported by a grant from the National Institute on Aging (AG04238, and the National Heart, Lung, and Blood Institute (HL30675).

Abstract

Objectives: To determine the effects of up to 14 months of aerobic exercise on measures of bone density in older adults.

Design: Randomized controlled trial with subjects assigned to either an aerobic exercise condition, non-aerobic yoga, or a wait list non-exercise control group for 4 months. Aerobic fitness and bone density were evaluated in all subjects at baseline (Time 1) and after 4 months (Time 2). A semi-crossover design was utilized with all subjects completing 4 months of aerobic exercise, followed by another evaluation (Time 3). All subjects were then given the option of 6 additional months of aerobic exercise, after which they had a fourth evaluation (Time 4).

Setting: An outpatient exercise rehabilitation facility at a large, major medical center.

Subjects: One-hundred-one healthy men (n = 50) and women (n = 51) over age 60 (Mean age = 67.0), recruited from the community.

Intervention: The exercise program included stretching, cycle ergometry, and walking three times per week for 60 minutes throughout the course of the study.

Outcome Measures: Aerobic fitness (VO2 max) as assessed by cycle ergometry, and bone density (bone mineral content) measured by single photon absorptiometry.

Results: Subjects achieved a 10%–15% increase in VO2 max after 4 months of exercise training, and 1%–6% further improvement with additional training. Aerobic fitness was associated with significant increases in bone density in men, but not women, who maintained aerobic exercise for 14 months.